The Archaeological Museum of Kalymnos is located at Pothia, at the district of Agia Triadha and was inaugurated in the year 2009 .The museum building was constructed by the Ministry of Culture, in a property donated for the purpose by the Solonian Home for the Elderly in 1997. In the same property is located the Vouvalis Mansion, an exceptional example of 19th century urban architecture, where a small part of the Prehistoric and Byzantine collection were previously housed.

It is located in the southern outskirts of the monastery of Aghioi Pantes and Aghios Savvas 1, 5 km from Pothia Town, in the region Vothynoi. It is a private Folklore Museum established by Mrs Faneromeni Skylla with objects of popular culture and household items of old houses.

It is located at the coastal village Vlichadia. It is a private museum, a life's work of Valsamidis brothers, who were born and live in Kalymnos, with exhibits related to sponge fishing, a big variety of sea plants and sea animals and a collection of trade amphorae and other finds from ancient shipwrecks.